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Gamma Cyclodextrin CAS 17465-86-0



γ-Cyclodextrin sometimes abbreviated as γ-CD, is an octasaccharide derived from glucose. The α- (alpha), β- (beta), and γ- (gamma) cyclodextrins correspond to six, seven, and eight glucose units, respectively.

 

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    Name Gamma cyclodextrin CAS 17465-86-0
    CAS No. 17465-86-0
    Molecular Formula C48H80O40
    Molecular Weight 1297.12
    Appearance White or almost whiteamorphous or crystalline powder.
    Assay 98%-102%
    Classification Pharmaceutical Grade
    quality standard Enterprise Standard

    Molecular structuer:

    In the field of Pharmaceutical:

    Gamma cyclodextrin CAS 17465-86-0 is mainly used to increase the solubility and stability of drugs. Cyclodextrin inclusion compounds with hydrophobic molecules are able to penetrate human tissues and can be used to release bioactive compounds under specific conditions. Enhance the mucosal permeability of the drug.

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    In γ-cyclodextrin, the eight glucose subunits are linked end to end via α-1,4 linkages. The result has the shape of a tapered cylinder, with 8 primary alcohols on one face and 16 secondary alcohol groups on the other. The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic.

    Q: What are the differences between the three basic cyclodextrins?

    A: Alpha cyclodextrin, beta cyclodextrin, and gamma cyclodextrin are the three commonly used basic cyclodextrins, and their raw materials are tapioca starch or corn starch. The difference is reflected in the following two points:
    First, the diameter of the cyclodextrin cavity is different;
    Second, the solubility of cyclodextrin in water is different.

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