Products

Zhiyuan has more than 70 varieties of cyclodextrin raw materials,
including cyclodextrin derivatives, cyclodextrin inclusion complexes,
cyclodextrin polymers, cyclodextrin reagents, and customized processing.


Carboxymethyl Beta Cyclodextrin CAS 218269-34-2



When pH<4, Carboxymethyl-β-Cyclodextrin (CM-β-CD) solubility is low in water. But when pH>4, Carboxyl Group Dissociate, CM-β-CD solubility becomes higher. It is very good for controlled release.

  • Quick Details

  • Product Introduction

  • Application

  • Packing & Storage

    Specifications
    Name Carboxymethyl beta cyclodextrin
    CAS No. 218269-34-2
    Synonyms Carboxymethyl-β-Cyclodextrin;

    Carboxymethyl beta cyclodextrin sodium salt;

    Molecular Formula C42H70-nO35· (CH2COONa)n
    Molecular Weight 1135.0+80 n
    Appearance White or light yellow powder, odorless
    Solubility of Carboxymethyl beta cyclodextrin
    Solvent Water Ethanol Acetone Ether Methanol DMF
    Solubility X<0.5ml 50ml≦X<500ml X>5000ml X>5000ml X>5000ml 15ml≦X<50ml
    Remark X means solubility.

    Temperature T=25 ℃,
    Quantity of solvents: 0.5g.
    Dissolve with the minimum amount of relevant reagents.

    Note: (Temperature T=25 ℃) Take 0.5g of solute and dissolve it with the minimum amount of corresponding reagent.

    Slightly soluble: 15ml≤ X<50ml Slightly soluble: 15ml ≤ X<50ml

    Extremely soluble: X<0.5ml Slightly soluble: 50ml ≤ X<500ml

    Soluble: 0.5ml ≤ X<5ml Very slightly soluble: 500ml ≤ X<5000ml

    Dissolution: 5ml ≤ X<15ml Insolubility: X>5000ml

     

    Carboxymethyl beta Cyclodextrin (carboxymethyl- β- Cyclodextrin) has low solubility in low pH solutions, but can be dissolved in neutral and alkaline solutions (pH>4) at any concentration, and its structure is loose, and its self mobility is greatly improved. It has good solubility in the environment of human intestinal pH 6-7, and can be used as drug prolonging release agent. It has lower hemolysis than hydroxypropyl beta Cyclodextrin.

    As chiral selectivity (or mobile phase chiral additive), it is used for the analysis of chiral compounds by high performance liquid chromatography or high performance capillary electrophoresis. It can be mainly applied to the resolution of chiral drugs such as Paroxetine and its intermediates, Barbital, steroids, quinolones and some amino acids.

     

    Shandong Binzhou Zhiyuan Biotechnology is a high-tech enterprise specializing in the research and production of Cyclodextrin and its derivatives. Relying on the Cyclodextrin Research Center of Shandong University, it has a strong technical force. We are equipped with advanced detection equipment, such as meteorological chromatograph, high-performance liquid chromatography, ion chromatograph, capillary electrophoresis, infrared spectrometer, one thousandth balance, trace moisture detector, and other imported detection instruments. The inspection methods are complete and can provide mass spectrometry, carbon spectroscopy, infrared spectroscopy, and nuclear magnetic resonance, providing strong support for product quality control and development research. Reliable quality and favorable prices have been recognized by customers both domestically and internationally.

    Shandong Binzhou Zhiyuan is committed to best customer services.

    1.Can assurance of product quality and safety.

    2.Can offer flexible packing options, such as 1g/ bottle, 2g/ bottle, 5g/ bottle, 10g/ bottle or or according to customers’ request. Including g to kg package sizes.

    3.Can accurate weighing service.

    4.Storage:

    Indoor in a cool and ventilated place, sealed for storage.

    5.Transportation method:via FEDEX, UPS, DHL etc.

    6.Validity period:two years.

Leading Manufacture And Solution Provider Of Cyclodextrin Derivatives