We uses molecular capsule technology to encapsulate azelaic acid into cyclodextrin cavity to form Water-soluble Azelaic acid inclusion complex. Its oil control performance is very excellent, avoiding the defects of azelaic acid: free azelaic acid has certain irritation effect on skin, eyes, mucous membrane and upper respiratory tract, and the water solubility of azelaic acid is poor, which is not conducive to use. While maintaining the function of azelaic acid, it improves water solubility and reduces irritation, which is more conducive to its use in skin medicine, cosmetics and care products.

Water-soluble Azelaic acid inclusion complex produced by Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. has a high content and is added less in skin care products. At room temperature, it is put into water to stir and dissolve, and the aqueous solution is clear and transparent.

Azelaic acid, not only treats acne and rosacea, but also has a certain effect on the stubborn melasma. Water-soluble Azelaic acid inclusion complex can not only inhibit the action of 5-alpha reductase, reduce the production of androgen DHT, so as to achieve the effect of oil control, but also inhibit the growth of bacteria, especially Propionibacterium acnes, regulate the growth of keratinocytes, and reduce the clogging of pores. . In addition, azelaic acid also has a good anti-inflammatory effect, so it can not only treat acne and acne marks, but also has excellent performance in the treatment of rosacea, that is, rosacea. This ingredient is neither water soluble nor oil soluble, and keeping it in solution is a test of formulation skill. When we use cyclodextrin inclusion, it can greatly improve the water solubility of azelaic acid and enrich its role in skin care products.