Methyl-β-cyclodextrin (beta-MCD)
Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin。It contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups.
Methyl-b-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes.
Methyl-β-cyclodextrin can reduces alpha synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein.
It also reduces alpha synuclein levels in mouse brain in a transgenic model of alpha synucleinopathy.
-
Quick Details
-
Product Specification
-
Application
-
Packing & Storage
-
FAQ
| Prodcut name | Methyl-β-cyclodextrin (beta-MCD) |
| MOQ | 1kg |
| Application | Cosmetic Grade or research purpose |
| Packing | As per your request |
| Storage | Preserve in tight,light-resistant containers in a cool place |
| Remarks | Enterprise standard |
| Custom synthesis | Available |
| Supply Ability | 50000kg/year |
| Name | Methyl beta cyclodextrin (MβCD) |
| CAS No. | 128446-36-6 |
| Molecular Formula | C42H70‐nO35.(CH3)n |
| Purity | 99% |
| Appearance | White powder, insipid, innocent |
| Assay | ≥98％ |
| Type | Syntheses Material Intermediates |
| quality standard | Enterprise Standard |
| Availability | In stock |
| Place of Origin | Shandong, China |
| Brand Name | Zhiyuan |
| Application | Food Addtive, Cosmetic,Food |
In the field of cosmetics, it can reduce the stimulation of model molecules in cosmetics to skin mucosal tissues, enhance the stability of substances, and prevent the volatilization and oxidation of nutrients.
Methyl beta cyclodextrin Application in Cosmetics feild:
◆ Sales:24 Hours Online Response Sharing Of Market information Trend Suggestion For Purchase Decision
◆ Payment:Different Payment Terms: TT,LC at sight, etc.
Multiple Payment Methods: Bank Transfer, Credit Card，Alipay,Etc.
Funds Risk Control
◆ Shipment Conditions:Fast Shipping Within 1-3 Working Days Usually,Update For Full Shipment Process From China To Destination.Cooperation For Fast&Smooth Custom Clearance At Destination
◆ Reputation: implementing Contract Terms Strictly,Timely Solving Any Discrepancy Or Goods Claims Responsible For Loss Under Our Liability
◆ Others:Assistant: send free sample;
Technology: Rich Experienced Technician To Support
● Internal packing: packed PE bag, then put into aluminum foil bag
● Storage: Preserve well-closed containers protect from moisture.
● Label: according to customers’ request.
● Outer packing: packed in drum.
Q: Is Zhiyuan methyl beta cyclodextrin of pharmaceutical grade?
A: The methyl beta cyclodextrin produced by Zhiyuan has been registered with China CDE, and the registration number is F20210000272. Since methyl beta cyclodextrin has not entered the pharmacopoeia at home and abroad, the product testing standards are corporate standards, but microbial indicators are controlled during the production process. Relevant companies are welcome to submit joint applications.
Q: What is the basic information about methyl beta cyclodextrin?
A:
A. Calculation of the molecular weight of methyl beta cyclodextrin: 1135+14n (n is the degree of substitution)
B. The solubility of methyl beta cyclodextrin in water is >100g/(100g water, 20℃), that is, 50% of the aqueous solution is clear.
C. The 50% aqueous solution is clear and colored.
D. The conductivity is similar to that of hydroxypropyl beta cyclodextrin. Theoretically it can reach about 10μs/cm, but the cost will be greatly increased. If customer service has requirements, you can refer to the USP standard of hydroxypropyl beta cyclodextrin ≤ 200 μS/cm.
E. Methyl beta cyclodextrin refers to substitution at positions 2, 3, and 6. If all positions 2, 3, and 6 are substituted, the degree of substitution is 21.
F. 2,6-dimethyl beta cyclodextrin refers to substitution at the 2,6 position, and its degree of substitution is 14.
G. The packaging is medicinal low-density polyethylene bags.
H. Methyl beta-cyclodextrin has high surface activity, and is a fat-soluble cyclodextrin with good skin permeability, which is beneficial to bringing active ingredients into the skin. Therefore, it is more effective than hydroxypropyl beta cyclodextrin in cosmetics. Please see the literature for more uses.
I. The existing vaccine pretreatment uses 2,6-dimethyl beta cyclodextrin.
