2, 6-Di-O-Methyl-Beta-Cyclodextrin
Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a cholesterol sequestering agent which modifies lipid rafts of the cell membrane. β-cyclodextrins are involved in cytotoxicity in various cells through complexation with cholesterol and membrane lipids.
Ionic forms of these molecules greatly reduce its cytoxicity compared to its methylated form. The cytotoxicity of β-cyclodextrins is affected by the position of the substitution of the methylated portion of the molecule.
The ability of a β-cyclodextrin to potentiate cytotoxic effects is dependent on the molecules ability to extract cholesterol from cell membranes. Alternate studies indicate that 2, 6-Di-O-Methyl-Beta-Cyclodextrin contains a stereoselective cavity only when the R substituent is linked to the chiral carbon which contains an aromatic ring.
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Product Specification
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Application
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Packing & Storage
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Delivery
| Name | Heptakis-2,6-di-O-methyl-beta-cyclodextrin |
| Application | Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a cholesterol sequestering cyclodextrin preparation |
| Colour | White |
| Shortage | Store in a Cool, Dry Place |
| Grade | Pharmaceutical Grade |
| Form | Powder |
| Transport Package | 1kg,10kg or according to our requirement |
| Trademark | Zhiyuan |
| Origin | Shandong |
| Production Capacity | 20000 Kg Per year |
Irst aid measures of 2,6-Di-O-methyl-β-cyclodextrin:
★Description of first aid measures
★If breathed in, move person into fresh air.
★In case of skin contact，Wash off with soap and plenty of water.
★In case of eye contact，Flush eyes with water as a precaution.
★If swallowed，Never give anything by mouth to an unconscious person. Rinse mouth with water.
Application of 2, 6-Di-O-Methyl-Beta-Cyclodextrin as below:
It has very high water solubility and oil solubility. As a matrix molecule used as an inclusion complex for the inclusion of drugs, spices, and other substances, it can completely change the properties of its original substance.
In medicine, it can promote the dissolution of drugs, improve drug solubility, bioavailability, and increase the efficacy or dosage of drugs. It can adjust or control the release rate of drugs, reduce drug toxicity and side effects, and enhance drug stability, It is more effective to change the absorption of drugs by the mucosa, especially to increase the water solubility of oil soluble molecules.
In daily chemicals and cosmetics, it can reduce microbial pollution, keep skin moist, mask bad smell, promote the transdermal absorption of Active ingredient, reduce skin irritation, etc.
Used for dyeing and finishing, chromatographic analysis, and functional materials in food, pesticides, chemical industry, and textiles
Packaging Details:
10kg/drum or by request of clients
Port:
Qingdao, Tiajin, Hangzhou,Beijing,Shanghai, etc.
Precautions for safe handling:
1.Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.
2.Conditions for safe storage, including any incompatibilities.
3.Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 20kg Fast: 3-7 days High cost Door to door service, Easy to pick up the goods |
Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed |
Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed |
